VGF

Across TCGA patient cohorts, VGF mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible VGF-associated genes across cancer lineages are NK cells and Memory B-cells. Each is linked with VGF in more than 1 cancer types. Because this analysis shows association rather than direction, both VGF-to-partner and partner-to-VGF results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NK cells grouped by VGF-low versus VGF-high in STAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VGF→partner) and Y-score (partner→VGF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	NK cells →	+0.011	+5.597	<.001	.040	3	1
UCEC	Memory B-cells →	+0.053	+2.374	.003	.039	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

NK cells by VGF expression — STAD

Explore this box plot interactively →