VEZF1

Across TCGA pan-cancer cohorts, VEZF1 Mutation is linked to patient survival in 6 of 34 cancer types, making it a survival-associated VEZF1 data layer compared with 27 for mass-spec protein and 4 for mass-spec protein.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher VEZF1 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated VEZF1 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

LUAD, UCEC, and HNSC are the cancer types where VEZF1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Median	II,III,IV	0.004	0.751	<.001	26	view →
UCEC	DFS	Median	All	0.958	0.624	.016	26	view →
HNSC	DFS	Median	IV	0.176	0.644	.005	21	view →
LIHC	DFS	Median	All	0.130	0.555	.014	6	view →
PRAD	DFS	Median	All	0.085	0.774	<.001	6	view →
LUSC	DFS	Median	All	0.136	0.791	.005	3	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

VEZF1–LUAD (OS)

Open the LUAD breakdown →