VEZF1

Across TCGA pan-cancer cohorts, VEZF1 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated VEZF1 data layer compared with 27 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher VEZF1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated VEZF1 expression acts as an unfavorable survival marker, although some lineages such as LSCC and LUAD show a favorable association.

HNSC, PDAC, and LSCC are the cancer types where VEZF1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Tertile	All	0.270	1.000	.008	23	view →
PDAC	OS	Quartile	II,III,IV	0.406	0.712	<.001	11	view →
LSCC	OS	Median	All	1.000	0.929	.022	8	view →
LUAD	DFS	Quartile	All	0.881	0.456	.009	8	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

VEZF1–HNSC (OS)

Open the HNSC breakdown →