Across TCGA cell cohorts, VEPH1 mutation is significantly associated with the RNA expression of many other genes, with 42 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible VEPH1-associated genes across cancer lineages are USP17L15, C1QC, and MAGEB5. Each is linked with VEPH1 in more than 1 cancer types. Because this analysis shows association rather than direction, both VEPH1-to-partner and partner-to-VEPH1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VEPH1→partner) and Y-score (partner→VEPH1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	USP17L15 →	+0.021	+4.635	.005	.003	3	2
LUNG_NSCLC_LUSC	C1QC →	+0.013	+4.643	<.001	.008	3	1
LUNG_NSCLC_LUSC	MAGEB5 →	+0.033	+4.643	<.001	.008	3	1
SOFT_TISSUE	HTR1E →	+0.167	+4.369	<.001	.008	3	1
SOFT_TISSUE	CCR8 →	+0.016	+4.369	<.001	.008	3	1
SOFT_TISSUE	GPR139 →	+0.016	+4.369	.004	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 42 associations by consensus.

Exploration

VEPH1 survival (RNA) · tumor vs normal (RNA) · all VEPH1 data types