VEGFB

Across TCGA cell cohorts, VEGFB mutation is significantly associated with the RNA expression of many other genes, with 178 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible VEGFB-associated genes across cancer lineages are TXN2, C1QBP, and LRRC59. Each is linked with VEGFB in more than 1 cancer types. Because this analysis shows association rather than direction, both VEGFB-to-partner and partner-to-VEGFB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TXN2 grouped by VEGFB-low versus VEGFB-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VEGFB→partner) and Y-score (partner→VEGFB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	TXN2 →	+0.551	+3.299	.003	.004	3	1
LARGE_INTESTINE	C1QBP →	+0.733	+3.299	.002	.004	3	1
LARGE_INTESTINE	LRRC59 →	+0.593	+3.212	.004	.006	3	1
LARGE_INTESTINE	NDUFAF4 →	+0.683	+3.212	.001	.006	3	1
LARGE_INTESTINE	MRPL34 →	+0.561	+3.212	.001	.006	3	1
LARGE_INTESTINE	SCLY →	+0.647	+3.212	.002	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 178 associations by consensus.

TXN2 by VEGFB expression — LARGE_INTESTINE

Explore this box plot interactively →