VDAC2P5

Across TCGA pan-cancer cohorts, VDAC2P5 RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated VDAC2P5 data layer.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher VDAC2P5 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated VDAC2P5 expression acts as an unfavorable survival marker, although some lineages such as KIRC and READ show a favorable association.

LUAD, OV, and KIRC are the cancer types where VDAC2P5 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Median	All	0.741	0.882	<.001	97	view →
OV	DFS	Median	II,III,IV	0.332	0.423	.004	44	view →
KIRC	DFS	Median	II,III,IV	0.759	0.545	.002	34	view →
ACC	DFS	Median	All	0.521	0.796	.001	30	view →
READ	DFS	Median	II,III,IV	0.645	0.366	.009	24	view →
MESO	OS	Quartile	IV	0.935	0.455	.008	12	view →
SKCM	DFS	Quartile	All	0.554	0.700	.012	10	view →
KICH	OS	Tertile	II,III,IV	0.527	1.000	.007	9	view →
BLCA	OS	Quartile	II,III,IV	0.330	0.581	.024	7	view →
BRCA	OS	Median	All	0.497	0.634	.011	7	view →
UCEC	DFS	Median	All	0.794	0.877	.005	6	view →
STAD	DFS	Tertile	IV	0.472	0.097	.017	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

VDAC2P5–LUAD (OS)

Open the LUAD breakdown →