VDAC2

Across TCGA patient cohorts, VDAC2 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,527 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible VDAC2-associated proteins across cancer lineages are DDX21, VDAC2_S115, and GLRX3. Each is linked with VDAC2 in more than 6 cancer types. Because this analysis shows association rather than direction, both VDAC2-to-partner and partner-to-VDAC2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, VDAC2 versus DDX21 in BRCA, with a Pearson correlation of 0.42.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (VDAC2→partner) and Y-score (partner→VDAC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	DDX21 →	+0.748	+0.538	<.001	<.001	3	7
LSCC	VDAC2_S115 →	+0.857	+0.758	<.001	<.001	3	6
LSCC	GLRX3 →	+0.425	+0.650	<.001	<.001	3	6
GBM	KIFBP →	+0.248	+0.264	<.001	<.001	3	6
LSCC	PSME4 →	+0.236	+0.558	.002	<.001	3	5
OV	NOP16 →	+0.538	+0.540	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,527 associations by consensus.

VDAC2 vs DDX21 — BRCA

Explore this scatter interactively →