VDAC2

Across TCGA patient cohorts, VDAC2 protein abundance is significantly associated with the RNA expression of many other genes, with 12,892 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible VDAC2-associated genes across cancer lineages are CARD8, CISD1, and F13A1. Each is linked with VDAC2 in more than 4 cancer types. Because this analysis shows association rather than direction, both VDAC2-to-partner and partner-to-VDAC2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, VDAC2 versus CARD8 in OV, with a Pearson correlation of -0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VDAC2→partner) and Y-score (partner→VDAC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CARD8 →	-0.545	-0.542	.005	<.001	3	5
CCRCC	CISD1 →	+0.566	+0.478	.001	<.001	3	5
BRCA	F13A1 →	-1.488	-0.472	<.001	<.001	3	5
OV	EMILIN2 →	-0.890	-0.480	<.001	.005	3	5
BRCA	CMAHP →	-0.849	-0.333	<.001	.002	3	5
UCEC	CAVIN1 →	-1.186	-0.656	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,892 associations by consensus.

VDAC2 vs CARD8 — OV

Explore this scatter interactively →