VDAC2

Across TCGA patient cohorts, VDAC2 mutation is significantly associated with the RNA expression of many other genes, with 237 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible VDAC2-associated genes across cancer lineages are RN7SL687P, RNA5SP204, and RNU6-764P. Each is linked with VDAC2 in more than 1 cancer types. Because this analysis shows association rather than direction, both VDAC2-to-partner and partner-to-VDAC2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL687P grouped by VDAC2-low versus VDAC2-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VDAC2→partner) and Y-score (partner→VDAC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RN7SL687P →	+0.331	+4.642	<.001	.004	3	2
UCEC	RNA5SP204 →	+0.371	+2.403	.004	.008	3	2
SKCM	RNU6-764P →	+0.324	+4.594	<.001	.008	3	2
SKCM	RNU6-434P →	+0.228	+4.513	.004	.009	3	2
BLCA	NIPA2P4 →	+0.062	+4.926	<.001	.002	3	1
BLCA	MIR3929 →	+0.702	+4.642	.003	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 237 associations by consensus.

RN7SL687P by VDAC2 expression — BLCA

Explore this box plot interactively →