VDAC1P6

Across TCGA patient cohorts, VDAC1P6 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,450 significant associations in total. PRAD shows the largest number of these associations.

The most reproducible VDAC1P6-associated GO terms across cancer lineages are Protein geranylgeranylation, Mitochondrial translational elongation, and Prenylation. Each is linked with VDAC1P6 in more than 22 cancer types. Because this analysis shows association rather than direction, both VDAC1P6-to-partner and partner-to-VDAC1P6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein geranylgeranylation grouped by VDAC1P6-low versus VDAC1P6-high in ACC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (VDAC1P6→partner) and Y-score (partner→VDAC1P6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ACC	Protein geranylgeranylation →	+0.053	+0.118	<.001	.002	2	23
UCS	Mitochondrial translational elongation →	+0.077	+0.156	<.001	.002	2	22
KICH	Prenylation →	+0.048	+0.136	<.001	<.001	3	19
UCS	Maturation of SSU-rRNA →	+0.056	+0.173	.001	.002	1	21
UCS	COPII-coated vesicle cargo loading →	+0.077	+0.138	.004	.004	1	21
ACC	XMP metabolic process →	+0.042	+0.103	.001	.003	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,450 associations by consensus.

Protein geranylgeranylation by VDAC1P6 expression — ACC

Explore this box plot interactively →