VDAC1P13

Across TCGA pan-cancer cohorts, VDAC1P13 RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated VDAC1P13 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher VDAC1P13 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated VDAC1P13 expression acts as an unfavorable survival marker, although some lineages such as BRCA and LIHC show a favorable association.

ACC, SKCM, and BRCA are the cancer types where VDAC1P13 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	OS	Tertile	All	0.225	0.706	<.001	165	view →
SKCM	OS	Tertile	All	0.801	0.893	<.001	66	view →
BRCA	DFS	Quartile	III,IV	0.962	0.849	.001	55	view →
COAD	DFS	Tertile	IV	0.271	0.522	.005	51	view →
UVM	DFS	Tertile	II,III,IV	0.112	0.770	<.001	42	view →
KIRP	OS	Tertile	All	0.842	0.950	.002	33	view →
LIHC	DFS	Tertile	III,IV	0.600	0.150	.020	24	view →
UCS	OS	Tertile	IV	0.253	0.691	.022	18	view →
MESO	OS	Tertile	IV	0.188	0.622	.021	18	view →
PCPG	DFS	Tertile	All	0.693	0.914	<.001	18	view →
LGG	OS	Tertile	All	0.535	0.846	<.001	18	view →
CHOL	DFS	Tertile	All	0.114	0.547	.005	15	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

VDAC1P13–ACC (OS)

Open the ACC breakdown →