VDAC1P1

Across TCGA patient cohorts, VDAC1P1 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,036 significant associations in total. PRAD shows the largest number of these associations.

The most reproducible VDAC1P1-associated GO terms across cancer lineages are Endoplasmic reticulum organization, Maturation of SSU-rRNA, and IMP metabolic process. Each is linked with VDAC1P1 in more than 25 cancer types. Because this analysis shows association rather than direction, both VDAC1P1-to-partner and partner-to-VDAC1P1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endoplasmic reticulum organization grouped by VDAC1P1-low versus VDAC1P1-high in UCS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (VDAC1P1→partner) and Y-score (partner→VDAC1P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCS	Endoplasmic reticulum organization →	+0.047	+0.813	<.001	<.001	3	26
ACC	Maturation of SSU-rRNA →	+0.056	+0.434	<.001	<.001	3	26
DLBC	IMP metabolic process →	+0.072	+0.327	<.001	<.001	3	26
THYM	Regulation of chromosome condensation →	+0.111	+0.286	<.001	.004	2	26
ACC	Mitochondrial translational elongation →	+0.085	+0.435	<.001	<.001	3	25
THYM	Protein modification by small protein removal →	+0.052	+0.455	<.001	<.001	3	25

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,036 associations by consensus.

Endoplasmic reticulum organization by VDAC1P1 expression — UCS

Explore this box plot interactively →