VCY1B

Across TCGA patient cohorts, VCY1B RNA expression is significantly associated with the go_rna of many other GO terms, with 1,258 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible VCY1B-associated GO terms across cancer lineages are Transcription by RNA polymerase I, Vitamin metabolic process, and Mitotic nuclear membrane organization. Each is linked with VCY1B in more than 2 cancer types. Because this analysis shows association rather than direction, both VCY1B-to-partner and partner-to-VCY1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Transcription by RNA polymerase I grouped by VCY1B-low versus VCY1B-high in SKCM.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (VCY1B→partner) and Y-score (partner→VCY1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	Transcription by RNA polymerase I →	+0.036	+0.034	<.001	<.001	3	2
PRAD	Vitamin metabolic process →	+0.026	+0.004	.005	.008	3	2
STAD	Mitotic nuclear membrane organization →	+0.052	+0.057	.002	.005	3	2
STAD	Negative regulation of tumor necrosis factor-mediated signaling pathway →	+0.037	+0.067	.001	.001	3	2
STAD	Negative regulation of cold-induced thermogenesis →	+0.035	+0.076	.005	.002	3	2
STAD	Positive regulation of mitotic sister chromatid separation →	+0.066	+0.093	.002	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,258 associations by consensus.

Transcription by RNA polymerase I by VCY1B expression — SKCM

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