VCX2

Across TCGA pan-cancer cohorts, VCX2 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of VCX2’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where VCX2 RNA is repressed in tumor relative to normal tissue. In most cancer types VCX2 is over-expressed in tumor, although a few such as KIRC and KIRP show the opposite, repressed pattern.

KIRC, HNSC, and LUAD are the cancer types where VCX2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in VCX2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Female	IV	−0.053	.012	3	view →
HNSC	All	All	+0.025	.020	2	view →
LUAD	All	All	+0.084	.035	1	view →
LUSC	All	All	+0.033	.010	1	view →
KIRP	Male	All	−0.031	.044	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

VCX2–KIRC

Open the KIRC breakdown →