VCPIP1

Across TCGA pan-cancer cohorts, VCPIP1 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated VCPIP1 data layer compared with 28 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher VCPIP1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated VCPIP1 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and LUAD show a favorable association.

HNSC, CCRCC, and LUAD are the cancer types where VCPIP1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Median	III,IV	0.779	0.912	.003	13	view →
CCRCC	OS	Median	III,IV	0.985	0.237	.017	9	view →
LUAD	DFS	Tertile	All	0.978	0.842	.018	9	view →
PDAC	OS	Tertile	IV	0.905	0.231	.024	4	view →
GBM	DFS	Tertile	All	0.214	0.451	.031	2	view →
LSCC	DFS	Quartile	All	0.609	1.000	.022	1	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

VCPIP1–HNSC (OS)

Open the HNSC breakdown →