VCAM1

Across TCGA pan-cancer cohorts, VCAM1 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated VCAM1 data layer compared with 23 for mass-spec protein and 8 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher VCAM1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated VCAM1 expression acts as an unfavorable survival marker, although some lineages such as LUAD and CCRCC show a favorable association.

COAD, UCEC, and LUAD are the cancer types where VCAM1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	II,III,IV	0.911	1.000	.012	36	view →
UCEC	DFS	Median	All	0.856	0.970	.017	10	view →
LUAD	DFS	Quartile	All	0.996	0.839	.009	8	view →
GBM	OS	Median	All	0.438	0.633	.026	5	view →
LSCC	DFS	Median	II,III,IV	0.547	0.824	.022	2	view →
CCRCC	DFS	Quartile	II,III,IV	1.000	0.849	.038	1	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

VCAM1–COAD (DFS)

Open the COAD breakdown →