VCAM1

Across TCGA cell cohorts, VCAM1 mutation is significantly associated with the RNA expression of many other genes, with 31 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible VCAM1-associated genes across cancer lineages are GUCA2A, C20orf85, and PRKACG. Each is linked with VCAM1 in more than 1 cancer types. Because this analysis shows association rather than direction, both VCAM1-to-partner and partner-to-VCAM1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GUCA2A grouped by VCAM1-low versus VCAM1-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VCAM1→partner) and Y-score (partner→VCAM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	GUCA2A →	+0.629	+3.695	.001	.005	3	2
SOFT_TISSUE	C20orf85 →	+0.115	+5.369	<.001	.004	3	1
SOFT_TISSUE	PRKACG →	+0.013	+5.369	<.001	.004	3	1
SOFT_TISSUE	OR4D6 →	+0.046	+5.977	<.001	.001	3	1
SOFT_TISSUE	OR51L1 →	+0.036	+5.369	<.001	.004	3	1
SOFT_TISSUE	OR51G2 →	+0.036	+5.369	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 31 associations by consensus.

GUCA2A by VCAM1 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →