VBP1

Across TCGA patient cohorts, VBP1 protein abundance is significantly associated with the RNA expression of many other genes, with 10,277 significant associations in total. GBM shows the largest number of these associations.

The most reproducible VBP1-associated genes across cancer lineages are CENPL, DKC1, and FLAD1. Each is linked with VBP1 in more than 5 cancer types. Because this analysis shows association rather than direction, both VBP1-to-partner and partner-to-VBP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, VBP1 versus CENPL in LUAD, with a Pearson correlation of 0.52.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VBP1→partner) and Y-score (partner→VBP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	CENPL →	+0.837	+0.309	<.001	<.001	3	6
UCEC	DKC1 →	+0.802	+0.229	<.001	<.001	3	6
LUAD	FLAD1 →	+0.509	+0.193	<.001	<.001	3	6
BRCA	UBE2Q1 →	+0.386	+0.281	.007	.001	3	6
BRCA	C1orf112 →	+0.589	+0.298	.001	<.001	3	6
OV	CSTF1 →	+0.434	+0.334	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,277 associations by consensus.

VBP1 vs CENPL — LUAD

Explore this scatter interactively →