VAX2

Across TCGA patient cohorts, VAX2 protein abundance is significantly associated with the RNA expression of many other genes, with 1,169 significant associations in total. GBM shows the largest number of these associations.

The most reproducible VAX2-associated genes across cancer lineages are CYTH4, HMOX1, and NCF4. Each is linked with VAX2 in more than 1 cancer types. Because this analysis shows association rather than direction, both VAX2-to-partner and partner-to-VAX2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, VAX2 versus CYTH4 in UCEC, with a Pearson correlation of 0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VAX2→partner) and Y-score (partner→VAX2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CYTH4 →	+1.197	+0.841	.001	.005	3	1
UCEC	HMOX1 →	+1.519	+0.732	.006	.006	3	1
UCEC	NCF4 →	+1.259	+0.899	.001	.001	3	1
UCEC	PLTP →	+1.235	+0.847	.007	.005	3	1
UCEC	CD40 →	+1.084	+0.901	.009	.007	3	1
UCEC	LIPG →	-1.375	-0.865	.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,169 associations by consensus.

VAX2 vs CYTH4 — UCEC

Explore this scatter interactively →