VAV3

Across TCGA patient cohorts, VAV3 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,117 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible VAV3-associated proteins across cancer lineages are TNKS1BP1_S178, TFB2M, and TNKS1BP1_S1073. Each is linked with VAV3 in more than 4 cancer types. Because this analysis shows association rather than direction, both VAV3-to-partner and partner-to-VAV3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, VAV3 versus TNKS1BP1_S178 in OV, with a Pearson correlation of 0.33.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (VAV3→partner) and Y-score (partner→VAV3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	TNKS1BP1_S178 →	+0.564	+1.586	.004	.006	3	4
HNSC	TFB2M →	-0.426	-0.741	<.001	.002	3	4
OV	TNKS1BP1_S1073 →	+0.675	+1.032	.002	.009	3	4
OV	PROM2 →	+0.537	+1.522	.006	.002	3	4
GBM	ARHGEF12 →	+0.203	+1.245	<.001	<.001	3	4
BRCA	TSR1 →	-0.384	-1.454	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,117 associations by consensus.

VAV3 vs TNKS1BP1_S178 — OV

Explore this scatter interactively →