VAV3

Across TCGA patient cohorts, VAV3 protein abundance is significantly associated with the RNA expression of many other genes, with 17,218 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible VAV3-associated genes across cancer lineages are CSF3R, C1QC, and CCR1. Each is linked with VAV3 in more than 5 cancer types. Because this analysis shows association rather than direction, both VAV3-to-partner and partner-to-VAV3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, VAV3 versus CSF3R in LSCC, with a Pearson correlation of 0.74.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VAV3→partner) and Y-score (partner→VAV3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	CSF3R →	+1.370	+0.355	<.001	<.001	3	6
LSCC	C1QC →	+0.871	+0.322	<.001	<.001	3	6
LSCC	CCR1 →	+0.829	+0.344	<.001	<.001	3	6
HNSC	SIRPB1 →	+0.600	+0.285	<.001	<.001	3	5
LSCC	MEFV →	+0.895	+0.400	<.001	<.001	3	5
LSCC	LILRB1 →	+0.781	+0.365	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,218 associations by consensus.

VAV3 vs CSF3R — LSCC

Explore this scatter interactively →