VAT1L

Across TCGA patient cohorts, VAT1L RNA expression is significantly associated with the protein abundance of many other proteins, with 10,042 significant associations in total. GBM shows the largest number of these associations.

The most reproducible VAT1L-associated proteins across cancer lineages are LOXL2, ACTN1, and C1R. Each is linked with VAT1L in more than 6 cancer types. Because this analysis shows association rather than direction, both VAT1L-to-partner and partner-to-VAT1L results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, VAT1L versus LOXL2 in LSCC, with a Pearson correlation of 0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (VAT1L→partner) and Y-score (partner→VAT1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	LOXL2 →	+1.286	+0.549	<.001	<.001	2	7
OV	ACTN1 →	+0.645	+0.859	<.001	<.001	3	5
OV	C1R →	+0.569	+0.531	<.001	<.001	3	5
OV	C8A →	+0.532	+0.557	<.001	.004	3	5
LSCC	CCN1 →	+0.881	+0.567	<.001	<.001	3	5
BRCA	CD93 →	+0.564	+0.409	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,042 associations by consensus.

VAT1L vs LOXL2 — LSCC

Explore this scatter interactively →