VAT1L

Across TCGA cell cohorts, VAT1L RNA expression is significantly associated with the go_rna of many other GO terms, with 1,145 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible VAT1L-associated GO terms across cancer lineages are Endoplasmic reticulum calcium ion homeostasis, Response to vitamin B1, and Regulation of cell adhesion involved in heart morphogenesis. Each is linked with VAT1L in more than 3 cancer types. Because this analysis shows association rather than direction, both VAT1L-to-partner and partner-to-VAT1L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endoplasmic reticulum calcium ion homeostasis grouped by VAT1L-low versus VAT1L-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (VAT1L→partner) and Y-score (partner→VAT1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Endoplasmic reticulum calcium ion homeostasis →	+0.102	+0.817	<.001	.006	3	4
BREAST	Response to vitamin B1 →	+0.103	+0.708	.002	.003	3	4
SKIN	Regulation of cell adhesion involved in heart morphogenesis →	+0.133	+1.311	<.001	.009	3	4
SKIN	Response to UV →	+0.041	+0.829	<.001	.007	3	4
LUNG_SCLC	Negative regulation of RNA splicing →	+0.082	+1.525	<.001	<.001	3	4
LUNG_SCLC	Negative regulation of mRNA processing →	+0.094	+1.977	.002	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,145 associations by consensus.

Endoplasmic reticulum calcium ion homeostasis by VAT1L expression — SKIN

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