VAT1L

Across TCGA cell cohorts, VAT1L mutation is significantly associated with the RNA expression of many other genes, with 21 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible VAT1L-associated genes across cancer lineages are GALNTL5, TAAR8, and HSF5. Each is linked with VAT1L in more than 1 cancer types. Because this analysis shows association rather than direction, both VAT1L-to-partner and partner-to-VAT1L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GALNTL5 grouped by VAT1L-low versus VAT1L-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VAT1L→partner) and Y-score (partner→VAT1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	GALNTL5 →	+0.054	+3.544	<.001	.009	3	1
LUNG_NSCLC_LUAD	TAAR8 →	+0.013	+4.078	<.001	.009	3	1
LUNG_NSCLC_LUAD	HSF5 →	+0.009	+3.977	<.001	.005	3	1
LUNG_NSCLC_LUAD	OR2L5 →	+0.013	+4.472	<.001	.001	3	1
LUNG_NSCLC_LUAD	SSX2 →	+0.922	+3.754	.001	.008	3	1
LARGE_INTESTINE	MS4A4A →	+0.242	+3.678	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 21 associations by consensus.

GALNTL5 by VAT1L expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →