VAT1

Across TCGA patient cohorts, VAT1 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,863 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible VAT1-associated proteins across cancer lineages are MAP1A, SEC11C, and IGFBP3. Each is linked with VAT1 in more than 6 cancer types. Because this analysis shows association rather than direction, both VAT1-to-partner and partner-to-VAT1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, VAT1 versus MAP1A in LSCC, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (VAT1→partner) and Y-score (partner→VAT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	MAP1A →	+0.604	+0.584	<.001	<.001	3	6
LUAD	SEC11C →	-0.872	-0.508	<.001	<.001	2	7
LSCC	IGFBP3 →	+0.766	+0.635	<.001	<.001	3	6
OV	ITGA5 →	+0.497	+0.690	.001	<.001	3	5
COAD	C1QC →	+0.817	+0.907	<.001	<.001	3	5
BRCA	ALG5 →	-0.429	-0.679	.003	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,863 associations by consensus.

VAT1 vs MAP1A — LSCC

Explore this scatter interactively →