VAT1

Across TCGA patient cohorts, VAT1 protein abundance is significantly associated with the RNA expression of many other genes, with 14,556 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible VAT1-associated genes across cancer lineages are CNRIP1, AOC3, and SCN7A. Each is linked with VAT1 in more than 7 cancer types. Because this analysis shows association rather than direction, both VAT1-to-partner and partner-to-VAT1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, VAT1 versus CNRIP1 in OV, with a Pearson correlation of 0.46.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VAT1→partner) and Y-score (partner→VAT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CNRIP1 →	+0.835	+0.542	<.001	<.001	3	8
BRCA	AOC3 →	+1.284	+0.290	.001	<.001	3	8
LSCC	SCN7A →	+1.191	+0.296	<.001	<.001	3	8
PDAC	RBMS3 →	+0.711	+0.239	<.001	<.001	3	8
OV	ZCCHC24 →	+1.219	+0.551	<.001	<.001	3	8
UCEC	PRKG1 →	+0.790	+0.231	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,556 associations by consensus.

VAT1 vs CNRIP1 — OV

Explore this scatter interactively →