VASN

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, VASN protein abundance is significantly associated with the RNA expression of many other genes, with 15,073 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible VASN-associated genes across cancer lineages are RARRES2, EDNRA, and PTH1R. Each is linked with VASN in more than 5 cancer types. Because this analysis shows association rather than direction, both VASN-to-partner and partner-to-VASN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, VASN versus RARRES2 in GBM, with a Pearson correlation of 0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VASN→partner) and Y-score (partner→VASN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMRARRES2 →+1.298+0.339<.001<.00136
OVEDNRA →+0.981+0.386.005.00236
OVPTH1R →+0.816+0.412<.001.00136
BRCAFSTL1 →+1.070+0.447<.001<.00136
OVMIR100HG →+1.256+0.536<.001<.00136
GBMGALNT15 →+1.242+0.384<.001<.00136
Each partner links to its Q-omics profile. Showing the 6 strongest of 15,073 associations by consensus.

VASN vs RARRES2 — GBM

Per-sample scatter of VASN vs RARRES2 in GBM (Pearson r = 0.38).

Explore this scatter interactively →

Exploration