VASN

Across TCGA patient cohorts, VASN mutation is significantly associated with the RNA expression of many other genes, with 773 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible VASN-associated genes across cancer lineages are RNA5SP414, OR5T2, and RNU6-192P. Each is linked with VASN in more than 1 cancer types. Because this analysis shows association rather than direction, both VASN-to-partner and partner-to-VASN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP414 grouped by VASN-low versus VASN-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VASN→partner) and Y-score (partner→VASN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RNA5SP414 →	+0.216	+8.471	<.001	.005	3	2
LIHC	OR5T2 →	+0.052	+7.169	<.001	<.001	3	2
UCEC	RNU6-192P →	+0.322	+3.115	<.001	.007	3	2
UCEC	RNU6-1149P →	+0.245	+2.765	.005	.005	3	2
CESC	LINC02559 →	+1.376	+6.342	<.001	.001	3	2
LIHC	DLGAP1-AS4 →	+0.068	+5.544	.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 773 associations by consensus.

RNA5SP414 by VASN expression — BRCA

Explore this box plot interactively →