VASH2

Across TCGA cell cohorts, VASH2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,162 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible VASH2-associated GO terms across cancer lineages are Positive regulation of DNA repair, Cell cycle phase transition, and Regulation of DNA repair. Each is linked with VASH2 in more than 14 cancer types. Because this analysis shows association rather than direction, both VASH2-to-partner and partner-to-VASH2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of DNA repair grouped by VASH2-low versus VASH2-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (VASH2→partner) and Y-score (partner→VASH2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Positive regulation of DNA repair →	+0.067	+1.050	<.001	<.001	3	15
SOFT_TISSUE	Cell cycle phase transition →	+0.074	+2.166	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Regulation of DNA repair →	+0.063	+0.471	<.001	.002	3	14
LUNG_NSCLC_LUSC	Positive regulation of double-strand break repair →	+0.069	+0.782	<.001	<.001	3	14
STOMACH	Epigenetic regulation of gene expression →	+0.060	+1.070	.003	.008	2	15
BONE	Mitotic cell cycle phase transition →	+0.086	+1.477	.005	<.001	2	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,162 associations by consensus.

Positive regulation of DNA repair by VASH2 expression — STOMACH

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