VASH1-AS1

Across TCGA pan-cancer cohorts, VASH1-AS1 RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of VASH1-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where VASH1-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types VASH1-AS1 is over-expressed in tumor, although a few such as KIRC and BRCA show the opposite, repressed pattern.

KIRC, HNSC, and STAD are the cancer types where VASH1-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in VASH1-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Female	II,III,IV	−0.356	<.001	11	view →
HNSC	All	All	+0.337	<.001	10	view →
STAD	All	II,III,IV	+0.472	<.001	6	view →
BRCA	Female	II,III,IV	−0.327	<.001	6	view →
COAD	All	II,III,IV	+0.346	.004	5	view →
LIHC	All	All	+0.282	<.001	5	view →
LUAD	All	II,III,IV	−0.317	.009	3	view →
CHOL	All	All	+0.826	.006	2	view →
ESCA	Male	All	+0.801	.007	2	view →
READ	Female	All	+0.554	.022	2	view →
PRAD	All	All	+0.262	<.001	2	view →
BLCA	Male	IV	−0.347	.032	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

VASH1-AS1–KIRC

Open the KIRC breakdown →