Across TCGA patient cohorts, VARS1 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,407 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible VARS1-associated proteins across cancer lineages are UTP15, XPO5, and SRPK1. Each is linked with VARS1 in more than 6 cancer types. Because this analysis shows association rather than direction, both VARS1-to-partner and partner-to-VARS1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (VARS1→partner) and Y-score (partner→VARS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	UTP15 →	+0.311	+0.761	<.001	<.001	3	7
LSCC	XPO5 →	+0.553	+0.684	<.001	<.001	3	7
UCEC	SRPK1 →	+0.397	+1.166	<.001	<.001	3	6
BRCA	TBL3 →	+0.298	+0.569	<.001	<.001	3	6
LUAD	WDR75 →	+0.337	+0.654	<.001	<.001	3	6
LSCC	NOL6 →	+0.353	+0.686	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,407 associations by consensus.

Exploration

VARS1 survival (RNA) · tumor vs normal (RNA) · all VARS1 data types