VAPB

Across TCGA pan-cancer cohorts, VAPB mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated VAPB data layer compared with 27 for mass-spec protein.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher VAPB mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated VAPB expression acts as an unfavorable survival marker, although some lineages such as COAD and GBM show a favorable association.

COAD, GBM, and LUAD are the cancer types where VAPB mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Tertile	All	1.000	0.879	.010	66	view →
GBM	OS	Median	All	0.671	0.417	.005	16	view →
LUAD	DFS	Median	II,III,IV	0.286	0.649	.007	16	view →
PDAC	OS	Median	II,III,IV	0.644	0.349	.001	13	view →
HNSC	DFS	Tertile	III,IV	0.898	0.680	.032	5	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

VAPB–COAD (DFS)

Open the COAD breakdown →