VAMP4

Across TCGA patient cohorts, VAMP4 protein abundance is significantly associated with the RNA expression of many other genes, with 6,610 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible VAMP4-associated genes across cancer lineages are MCM2, RAD54L, and CYCSP52. Each is linked with VAMP4 in more than 2 cancer types. Because this analysis shows association rather than direction, both VAMP4-to-partner and partner-to-VAMP4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, VAMP4 versus MCM2 in COAD, with a Pearson correlation of -0.48.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VAMP4→partner) and Y-score (partner→VAMP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	MCM2 →	-1.158	-0.317	<.001	.007	3	3
COAD	RAD54L →	-0.856	-0.364	.002	.003	3	3
UCEC	CYCSP52 →	+0.922	+0.425	.001	.001	3	3
LSCC	KIFAP3 →	+0.465	+0.295	.002	.003	3	3
HNSC	TRAV26-1 →	-0.727	-0.221	<.001	.002	3	3
CCRCC	CCDC8 →	-1.258	-0.210	.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,610 associations by consensus.

VAMP4 vs MCM2 — COAD

Explore this scatter interactively →