VAMP4

Across TCGA cell cohorts, VAMP4 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,421 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible VAMP4-associated GO terms across cancer lineages are Golgi vesicle transport, Endoplasmic reticulum to Golgi vesicle-mediated transport, and Golgi organization. Each is linked with VAMP4 in more than 13 cancer types. Because this analysis shows association rather than direction, both VAMP4-to-partner and partner-to-VAMP4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Golgi vesicle transport grouped by VAMP4-low versus VAMP4-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (VAMP4→partner) and Y-score (partner→VAMP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Golgi vesicle transport →	+0.070	+0.964	<.001	<.001	3	14
SOFT_TISSUE	Endoplasmic reticulum to Golgi vesicle-mediated transport →	+0.074	+1.111	.001	.001	3	13
STOMACH	Golgi organization →	+0.081	+1.000	<.001	.001	2	13
STOMACH	Regulation of translational initiation →	+0.077	+0.747	.001	.003	3	12
SOFT_TISSUE	Vesicle-mediated transport to the plasma membrane →	+0.057	+1.309	<.001	.001	3	12
BONE	Vesicle budding from membrane →	+0.066	+0.883	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,421 associations by consensus.

Golgi vesicle transport by VAMP4 expression — PANCREAS

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