VAMP1

Across TCGA patient cohorts, VAMP1 protein abundance is significantly associated with the RNA expression of many other genes, with 3,341 significant associations in total. GBM shows the largest number of these associations.

The most reproducible VAMP1-associated genes across cancer lineages are NEFH, KIRREL1, and PRODH. Each is linked with VAMP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both VAMP1-to-partner and partner-to-VAMP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, VAMP1 versus NEFH in GBM, with a Pearson correlation of 0.58.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VAMP1→partner) and Y-score (partner→VAMP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	NEFH →	+1.249	+0.915	<.001	<.001	3	2
GBM	KIRREL1 →	-0.492	-0.642	.001	<.001	3	2
GBM	PRODH →	+0.806	+0.833	<.001	<.001	3	1
GBM	GRK3 →	+0.345	+0.504	.002	.005	3	1
GBM	SOX10 →	+1.169	+0.700	<.001	<.001	3	1
GBM	SLC16A8 →	+0.557	+0.706	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,341 associations by consensus.

VAMP1 vs NEFH — GBM

Explore this scatter interactively →