VAMP1

Across TCGA cell cohorts, VAMP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,287 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible VAMP1-associated GO terms across cancer lineages are Calcium-independent cell-matrix adhesion, mRNA splice site recognition, and Microtubule nucleation. Each is linked with VAMP1 in more than 14 cancer types. Because this analysis shows association rather than direction, both VAMP1-to-partner and partner-to-VAMP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Calcium-independent cell-matrix adhesion grouped by VAMP1-low versus VAMP1-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (VAMP1→partner) and Y-score (partner→VAMP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Calcium-independent cell-matrix adhesion →	+0.180	+1.055	<.001	.005	3	14
OVARY	mRNA splice site recognition →	+0.117	+0.925	<.001	.009	3	13
LARGE_INTESTINE	Microtubule nucleation →	+0.099	+0.921	<.001	<.001	3	13
OESOPHAGUS	Cytosolic transport →	+0.067	+0.950	.008	.007	1	15
OESOPHAGUS	Protein sumoylation →	+0.083	+1.196	.001	.004	3	13
BREAST	Negative regulation of calcium ion export across plasma membrane →	+0.108	+1.433	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,287 associations by consensus.

Calcium-independent cell-matrix adhesion by VAMP1 expression — URINARY_TRACT

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