VAC14

Across TCGA cell cohorts, VAC14 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,663 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible VAC14-associated GO terms across cancer lineages are Nuclear export, RNA export from nucleus, and Peptidyl-methionine modification. Each is linked with VAC14 in more than 11 cancer types. Because this analysis shows association rather than direction, both VAC14-to-partner and partner-to-VAC14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nuclear export grouped by VAC14-low versus VAC14-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (VAC14→partner) and Y-score (partner→VAC14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Nuclear export →	+0.070	+0.888	.001	<.001	3	12
BREAST	RNA export from nucleus →	+0.085	+1.027	.005	<.001	3	12
BREAST	Peptidyl-methionine modification →	+0.198	+0.784	.001	.005	3	11
UPPER_AERODIGESTIVE_TRACT	Lysosome organization →	+0.075	+0.683	<.001	.003	3	11
UPPER_AERODIGESTIVE_TRACT	Lytic vacuole organization →	+0.075	+0.683	<.001	.003	3	11
BREAST	mRNA alternative polyadenylation →	+0.094	+0.881	.002	.002	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,663 associations by consensus.

Nuclear export by VAC14 expression — BLOOD_Lymphoma

Explore this box plot interactively →