UVSSA

Across TCGA cell cohorts, UVSSA RNA expression is significantly associated with the go_rna of many other GO terms, with 4,389 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible UVSSA-associated GO terms across cancer lineages are Transcription pausing by RNA polymerase II, Cytosolic transport, and Regulation of aggrephagy. Each is linked with UVSSA in more than 17 cancer types. Because this analysis shows association rather than direction, both UVSSA-to-partner and partner-to-UVSSA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Transcription pausing by RNA polymerase II grouped by UVSSA-low versus UVSSA-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UVSSA→partner) and Y-score (partner→UVSSA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Transcription pausing by RNA polymerase II →	+0.161	+1.032	<.001	<.001	3	18
UPPER_AERODIGESTIVE_TRACT	Cytosolic transport →	+0.076	+1.494	.002	.001	3	16
BONE	Regulation of aggrephagy →	+0.170	+1.553	<.001	<.001	3	16
URINARY_TRACT	Cilium movement involved in cell motility →	-0.129	-1.462	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Cilium or flagellum-dependent cell motility →	-0.102	-1.202	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Negative regulation of myoblast fusion →	+0.121	+1.196	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,389 associations by consensus.

Transcription pausing by RNA polymerase II by UVSSA expression — BONE

Explore this box plot interactively →