Across TCGA pan-cancer cohorts, UVRAG mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated UVRAG data layer compared with 25 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher UVRAG mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated UVRAG expression acts as an unfavorable survival marker, although some lineages such as LUAD and PDAC show a favorable association.

LUAD, PDAC, and CCRCC are the cancer types where UVRAG mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Tertile	All	0.824	0.475	.001	38	view →
PDAC	DFS	Median	III,IV	0.870	0.501	.001	35	view →
CCRCC	DFS	Median	II,III,IV	0.732	0.485	.011	5	view →
HNSC	DFS	Quartile	II,III,IV	0.912	1.000	.036	3	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: UVRAG tumor-vs-normal RNA expression · all UVRAG data types