Across TCGA patient cohorts, UVRAG mutation is significantly associated with the total protein of many other genes, with 25 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible UVRAG-associated genes across cancer lineages are 14-3-3_beta, EGFR_pY1068, and eIF4E. Each is linked with UVRAG in more than 1 cancer types. Because this analysis shows association rather than direction, both UVRAG-to-partner and partner-to-UVRAG results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UVRAG→partner) and Y-score (partner→UVRAG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	14-3-3_beta →	-0.099	-2.558	.006	.010	3	1
UCEC	EGFR_pY1068 →	-0.217	-1.906	.016	.015	3	1
UCEC	eIF4E →	+0.166	+2.321	.028	.001	3	1
UCEC	JNK_pT183_Y185 →	-0.125	-2.459	.039	.019	3	1
UCEC	MSH2 →	-0.190	-1.848	.022	.049	3	1
UCEC	p27_pT198 →	+0.106	+1.925	.005	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 25 associations by consensus.

Exploration

UVRAG survival (RNA) · tumor vs normal (RNA) · all UVRAG data types