Across TCGA patient cohorts, UTY mutation is significantly associated with the RNA expression of many other genes, with 93 significant associations in total. BLCA shows the largest number of these associations.

The most reproducible UTY-associated genes across cancer lineages are RNU6-268P, ZNF736P7Y, and RNU6-758P. Each is linked with UTY in more than 1 cancer types. Because this analysis shows association rather than direction, both UTY-to-partner and partner-to-UTY results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UTY→partner) and Y-score (partner→UTY) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RNU6-268P →	+0.176	+3.301	.001	.007	3	2
COAD	ZNF736P7Y →	+0.087	+5.251	<.001	.003	3	2
COAD	RNU6-758P →	+0.787	+4.181	<.001	.009	3	2
COAD	NXF2 →	+0.056	+6.707	<.001	<.001	3	2
BLCA	MIR1323 →	+0.328	+5.466	<.001	.001	3	2
BLCA	PPIAP88 →	+0.069	+3.134	.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 93 associations by consensus.

Exploration

UTY survival (RNA) · tumor vs normal (RNA) · all UTY data types