UTS2

Across TCGA cell cohorts, UTS2 mutation is significantly associated with the mutation status of many other genes, with 1,407 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible UTS2-associated genes across cancer lineages are UPB1, SNRPD3, and LRP5L. Each is linked with UTS2 in more than 1 cancer types. Because this analysis shows association rather than direction, both UTS2-to-partner and partner-to-UTS2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, UPB1 grouped by UTS2-low versus UTS2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UTS2→partner) and Y-score (partner→UTS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	UPB1 →	+3.350	+4.584	.003	.003	1	1
LARGE_INTESTINE	SNRPD3 →	+5.087	+4.523	.006	.006	1	1
LARGE_INTESTINE	LRP5L →	+4.087	+5.044	.001	.001	1	1
LARGE_INTESTINE	SLC25A1 →	+3.672	+4.799	.002	.002	1	1
LARGE_INTESTINE	PLA2G3 →	+2.865	+4.217	.007	.007	1	1
LARGE_INTESTINE	SH3BP1 →	+4.672	+5.329	<.001	<.001	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,407 associations by consensus.

UPB1 by UTS2 expression — LARGE_INTESTINE

Explore this box plot interactively →