UTP6

Across TCGA pan-cancer cohorts, UTP6 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated UTP6 data layer compared with 23 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher UTP6 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated UTP6 expression acts as an unfavorable survival marker, although some lineages such as LSCC and LUAD show a favorable association.

CCRCC, PDAC, and LSCC are the cancer types where UTP6 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Tertile	III,IV	0.397	0.823	<.001	48	view →
PDAC	DFS	Median	All	0.588	0.836	.006	9	view →
LSCC	DFS	Quartile	All	0.907	0.567	.007	9	view →
LUAD	OS	Quartile	III,IV	0.861	0.194	.026	9	view →
HNSC	OS	Median	All	0.794	0.898	.029	5	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

UTP6–CCRCC (OS)

Open the CCRCC breakdown →