UTP4

Across TCGA pan-cancer cohorts, UTP4 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated UTP4 data layer compared with 27 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher UTP4 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated UTP4 expression acts as an unfavorable survival marker, although some lineages such as LSCC and GBM show a favorable association.

CCRCC, PDAC, and LUAD are the cancer types where UTP4 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Median	III,IV	0.720	1.000	<.001	74	view →
PDAC	DFS	Tertile	II,III,IV	0.295	0.565	.004	20	view →
LUAD	OS	Median	II,III,IV	0.336	1.000	<.001	18	view →
LSCC	DFS	Quartile	II,III,IV	0.878	0.444	.009	15	view →
GBM	DFS	Median	All	0.483	0.262	.012	5	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

UTP4–CCRCC (DFS)

Open the CCRCC breakdown →