UTP4

Across TCGA cell cohorts, UTP4 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,494 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible UTP4-associated GO terms across cancer lineages are DNA replication initiation, rRNA metabolic process, and Maturation of SSU-rRNA. Each is linked with UTP4 in more than 18 cancer types. Because this analysis shows association rather than direction, both UTP4-to-partner and partner-to-UTP4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA replication initiation grouped by UTP4-low versus UTP4-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UTP4→partner) and Y-score (partner→UTP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	DNA replication initiation →	+0.167	+1.410	<.001	<.001	3	19
LUNG_SCLC	rRNA metabolic process →	+0.101	+0.719	.001	.002	3	18
UPPER_AERODIGESTIVE_TRACT	Maturation of SSU-rRNA →	+0.137	+0.867	<.001	.001	3	18
UPPER_AERODIGESTIVE_TRACT	Ribosomal small subunit biogenesis →	+0.111	+0.853	<.001	<.001	3	18
BLOOD_Lymphoma	rRNA processing →	+0.106	+1.254	<.001	<.001	3	18
LIVER	Ribosomal large subunit biogenesis →	+0.118	+0.712	.002	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,494 associations by consensus.

DNA replication initiation by UTP4 expression — BLOOD_Myeloma

Explore this box plot interactively →