UTP25

Across TCGA patient cohorts, UTP25 mutation is significantly associated with the RNA expression of many other genes, with 3,713 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible UTP25-associated genes across cancer lineages are MIR4774, RNA5SP263, and LINC01496. Each is linked with UTP25 in more than 1 cancer types. Because this analysis shows association rather than direction, both UTP25-to-partner and partner-to-UTP25 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR4774 grouped by UTP25-low versus UTP25-high in READ.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UTP25→partner) and Y-score (partner→UTP25) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
READ	MIR4774 →	+0.841	+6.257	<.001	.001	3	2
HNSC	RNA5SP263 →	+0.541	+4.221	<.001	.009	3	2
HNSC	LINC01496 →	+0.176	+4.780	<.001	.003	3	2
HNSC	TNPO3P1 →	+0.068	+4.655	<.001	.007	3	2
HNSC	MIR8076 →	+0.356	+5.008	<.001	.004	3	2
CESC	LINC02329 →	+0.051	+6.000	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,713 associations by consensus.

MIR4774 by UTP25 expression — READ

Explore this box plot interactively →