UTP25

Across TCGA cell cohorts, UTP25 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,846 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible UTP25-associated GO terms across cancer lineages are RNA 3'-end processing, Transcription initiation at RNA polymerase I promoter, and Regulation of formation of translation preinitiation complex. Each is linked with UTP25 in more than 15 cancer types. Because this analysis shows association rather than direction, both UTP25-to-partner and partner-to-UTP25 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA 3'-end processing grouped by UTP25-low versus UTP25-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UTP25→partner) and Y-score (partner→UTP25) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	RNA 3'-end processing →	+0.059	+0.658	.004	.005	3	16
LARGE_INTESTINE	Transcription initiation at RNA polymerase I promoter →	+0.142	+0.570	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Regulation of formation of translation preinitiation complex →	+0.087	+0.648	<.001	.001	3	14
UPPER_AERODIGESTIVE_TRACT	Negative regulation of formation of translation preinitiation complex →	+0.087	+0.648	<.001	.001	3	14
BLOOD_Lymphoma	Ribosomal large subunit biogenesis →	+0.076	+0.527	<.001	<.001	3	14
OESOPHAGUS	Endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.113	+0.509	.002	.005	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,846 associations by consensus.

RNA 3'-end processing by UTP25 expression — PANCREAS

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