UTP25

Across TCGA cell cohorts, UTP25 mutation is significantly associated with the RNA expression of many other genes, with 414 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible UTP25-associated genes across cancer lineages are OR13G1, PRM2, and DRD3. Each is linked with UTP25 in more than 1 cancer types. Because this analysis shows association rather than direction, both UTP25-to-partner and partner-to-UTP25 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR13G1 grouped by UTP25-low versus UTP25-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UTP25→partner) and Y-score (partner→UTP25) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	OR13G1 →	+0.056	+4.189	<.001	.002	3	2
BLOOD_Leukemia	PRM2 →	+0.035	+5.969	<.001	.001	3	1
BLOOD_Leukemia	DRD3 →	+0.019	+5.201	<.001	.006	3	1
BLOOD_Leukemia	SPPL2C →	+0.012	+4.922	<.001	.009	3	1
LUNG_NSCLC_LUAD	LUZP4 →	+0.031	+4.215	.001	.002	3	1
LUNG_NSCLC_LUAD	H2BW1 →	+0.342	+4.628	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 414 associations by consensus.

OR13G1 by UTP25 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →