UTP23

Across TCGA cell cohorts, UTP23 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,078 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible UTP23-associated GO terms across cancer lineages are Positive regulation of DNA-directed DNA polymerase activity, Protein localization to condensed chromosome, and Replication fork processing. Each is linked with UTP23 in more than 14 cancer types. Because this analysis shows association rather than direction, both UTP23-to-partner and partner-to-UTP23 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of DNA-directed DNA polymerase activity grouped by UTP23-low versus UTP23-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UTP23→partner) and Y-score (partner→UTP23) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Positive regulation of DNA-directed DNA polymerase activity →	+0.204	+0.857	.001	.001	3	15
UPPER_AERODIGESTIVE_TRACT	Protein localization to condensed chromosome →	+0.138	+1.066	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Replication fork processing →	+0.074	+0.810	.001	<.001	3	14
KIDNEY	Mitotic sister chromatid cohesion →	+0.090	+0.406	.002	.003	3	14
STOMACH	miRNA-mediated gene silencing by mRNA destabilization →	+0.142	+0.845	.001	.001	3	14
UPPER_AERODIGESTIVE_TRACT	Transcription by RNA polymerase I →	+0.109	+1.243	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,078 associations by consensus.

Positive regulation of DNA-directed DNA polymerase activity by UTP23 expression — BONE

Explore this box plot interactively →