UTP18

Across TCGA cell cohorts, UTP18 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,722 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible UTP18-associated GO terms across cancer lineages are DNA replication initiation, DNA-templated DNA replication, and Lagging strand elongation. Each is linked with UTP18 in more than 17 cancer types. Because this analysis shows association rather than direction, both UTP18-to-partner and partner-to-UTP18 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA replication initiation grouped by UTP18-low versus UTP18-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UTP18→partner) and Y-score (partner→UTP18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	DNA replication initiation →	+0.168	+0.703	.002	.004	3	18
UPPER_AERODIGESTIVE_TRACT	DNA-templated DNA replication →	+0.110	+0.765	<.001	<.001	3	17
SOFT_TISSUE	Lagging strand elongation →	+0.158	+0.748	<.001	<.001	3	17
BLOOD_Myeloma	Formation of extrachromosomal circular DNA →	+0.085	+0.848	.006	<.001	3	16
PANCREAS	Meiotic cell cycle →	+0.090	+0.879	<.001	<.001	3	16
BONE	Nuclear DNA replication →	+0.145	+0.540	<.001	.002	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,722 associations by consensus.

DNA replication initiation by UTP18 expression — BONE

Explore this box plot interactively →